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A European multicentre PET study of fibrillar amyloid in Alzheimer's disease.

Abstract:

PURPOSE: Amyloid PET tracers have been developed for in vivo detection of brain fibrillar amyloid deposition in Alzheimer's disease (AD). To serve as an early biomarker in AD the amyloid PET tracers need to be analysed in multicentre clinical studies. METHODS: In this study 238 [(11)C]Pittsburgh compound-B (PIB) datasets from five different European centres were pooled. Of these 238 datasets, 18 were excluded, leaving [(11)C]PIB datasets from 97 patients with clinically diagnosed AD (mean age...

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Publisher copy:
10.1007/s00259-012-2237-2

Authors


Nordberg, A More by this author
Carter, SF More by this author
Drzezga, A More by this author
Brooks, DJ More by this author
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Journal:
European journal of nuclear medicine and molecular imaging
Volume:
40
Issue:
1
Pages:
104-114
Publication date:
2013-01-05
DOI:
EISSN:
1619-7089
ISSN:
1619-7070
URN:
uuid:52d54be7-5650-4b0f-8147-f95cd4097b15
Source identifiers:
429449
Local pid:
pubs:429449

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