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Studies on monocytes in inflammatory bowel disease: factors influencing monocyte lysosomal enzyme activity.

Abstract:

The effect of endotoxin and immune complexes on monocyte lysosomal enzyme activity has been studied in patients with Crohn's disease and ulcerative colitis. Immune complexes made at equivalence or in antigen excess caused a rapid fall in intracellular activity of the enzyme N'acetyl-beta-D-glucosaminidase which was significantly greater than that seen when cells were incubated with medium alone. Endotoxin had no effect on intracellular enzyme activity but there was a significant elevation of ...

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Publication status:
Published

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Authors


Nuttall, L More by this author
Potter, BJ More by this author
Jewell, DP More by this author
Journal:
Clinical and experimental immunology
Volume:
39
Issue:
3
Pages:
785-791
Publication date:
1980-03-05
EISSN:
1365-2249
ISSN:
0009-9104
URN:
uuid:52d42b43-8614-4898-8a28-bc20f908686d
Source identifiers:
165680
Local pid:
pubs:165680

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