Journal article
Identification of a bifunctional lipopolysaccharide sialyltransferase in Haemophilus influenzae: incorporation of disialic acid.
- Abstract:
-
The lipopolysaccharide (LPS) of non-typeable Haemophilus influenzae (NTHi) can be substituted at various positions by N-acetylneuraminic acid (Neu5Ac). LPS sialylation plays an important role in pathogenesis. The only LPS sialyltransferase characterized biochemically to date in H. influenzae is Lic3A, an alpha-2,3-sialyltransferase responsible for the addition of Neu5Ac to a lactose acceptor (Hood, D. W., Cox, A. D., Gilbert, M., Makepeace, K., Walsh, S., Deadman, M. E., Cody, A., Martin, A.,...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Journal of biological chemistry
- Volume:
- 281
- Issue:
- 52
- Pages:
- 40024-40032
- Publication date:
- 2006-12-01
- DOI:
- EISSN:
-
1083-351X
- ISSN:
-
0021-9258
- Source identifiers:
-
115597
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:115597
- UUID:
-
uuid:52c9397c-44e0-4adc-afcc-f8ba6429baf9
- Local pid:
- pubs:115597
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2006
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