- Abstract:
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An effective therapeutic vaccine for the treatment of chronic hepatitis C virus (HCV) infection, as an adjunct to newly developed directly-acting antivirals (DAA), or for the prevention of reinfection would significantly reduce the global burden of disease associated with chronic HCV infection.
Expand abstract
A recombinant chimpanzee adenoviral (ChAd3) vector and a modified vaccinia Ankara (MVA), encoding the non-structural proteins of HCV (NSmut), used in a heterologous prime/boost regimen induc... - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 3.7mb)
-
- Publisher copy:
- 10.3390/vaccines4030027
-
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- Publisher:
- MDPI Publisher's website
- Journal:
- Vaccines Journal website
- Publication date:
- 2016-08-02
- DOI:
- ISSN:
-
2076-393X
- URN:
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uuid:5281d872-bdf3-44e4-baf0-c5f54c9e842c
- Source identifiers:
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634778
- Local pid:
- pubs:634778
- Copyright holder:
- Swadling et al.
- Copyright date:
- 2016
- Notes:
- © 2016 by the author; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license.
Journal article
Highly immunogenic virally vectored T-cell vaccines cannot overcome subversion of the T-cell response by HCV during chronic infection
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