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Journal article

Subcortical evoked activity and motor enhancement in Parkinson's disease

Abstract:

Enhancements in motor performance have been demonstrated in response to intense stimuli both in healthy subjects and in the form of ‘paradoxical kinesis’ in patients with Parkinson's disease. Here we identify a mid-latency evoked potential in local field potential recordings from the region of the subthalamic nucleus, which scales in amplitude with both the intensity of the stimulus delivered and corresponding enhancements in biomechanical measures of maximal handgrips, independent of the dop...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.expneurol.2015.12.004

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
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Cure Parkinson's Trust More from this funder
National Institute of Health Research Oxford Biomedical Research Centre More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Experimental Neurology Journal website
Volume:
277
Pages:
19–26
Publication date:
2016-01-01
DOI:
ISSN:
1090-2430
Source identifiers:
580283
Keywords:
Pubs id:
pubs:580283
UUID:
uuid:526bfa92-d382-4558-9172-cbacb018da89
Local pid:
pubs:580283
Deposit date:
2015-12-20

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