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The cardiovascular effect of incretin-based therapies among type 2 diabetes: a systematic review and network meta-analysis

Abstract:

Objective: To evaluate the comparative cardiovascular safety of incretin-based therapies in patients with type 2 diabetes mellitus (T2DM).

Methods: Medline, Embase, the Cochrane Library and www.clinicaltrials.gov were searched for randomized controlled trials (RCTs) with duration≥12 weeks. Network meta-analysis was performed, followed by subgroup analysis and meta-regression. The Grading of Recommendations Assessment, Development and Evaluation syst...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1080/14740338.2018.1424826

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Psychiatry
ORCID:
0000-0001-5179-8321
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Publisher:
Taylor and Francis Publisher's website
Journal:
Expert Opinion on Drug Safety Journal website
Volume:
17
Issue:
3
Pages:
243-249
Publication date:
2018-01-10
Acceptance date:
2018-01-03
DOI:
EISSN:
1744-764X
ISSN:
1474-0338
Pubs id:
pubs:820778
URN:
uri:5250e0ff-e204-4abd-a54e-dc845b5affac
UUID:
uuid:5250e0ff-e204-4abd-a54e-dc845b5affac
Local pid:
pubs:820778

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