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Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus - Progressive requirement for multiple therapies (UKPDS 49)

Abstract:

Context Treatment with diet alone, insulin, sulfonylurea, or metformin is known to improve glycemia in patients with type 2 diabetes mellitus, but which treatment most frequently attains target fasting plasma glucose (FPG) concentration of less than 7.8 mmol/L (140 mg/dL) or glycosylated hemoglobin A(1c) (HbA(1c)) below 7% is unknown. Objective To assess how often each therapy can achieve the glycemic control target levels set by the American Diabetes Association. Design Randomized controlled...

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Publication status:
Published

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Publisher copy:
10.1001/jama.281.21.2005

Authors


Turner, RC More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM, Biomedical Research Centre
Grp, UKPDS More by this author
Journal:
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Volume:
281
Issue:
21
Pages:
2005-2012
Publication date:
1999-06-02
DOI:
ISSN:
0098-7484
URN:
uuid:52411c5e-bdea-49d3-874d-2f93d9889988
Source identifiers:
841
Local pid:
pubs:841

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