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Enigmatic variations: divergent modes of regulating eukaryotic DNA replication.

Abstract:
Proteins involved in DNA replication are conserved from yeast to mammals, suggesting that the mechanism was established at an early stage of eukaryotic evolution. In spite of this common origin, recent findings have revealed surprising variations in how replication initiation is controlled, implying that a conserved mechanism has not necessarily resulted in regulatory conservation.
Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
Cotterill, S More by this author
Journal:
Molecular cell
Volume:
12
Issue:
5
Pages:
1067-1075
Publication date:
2003-11-05
DOI:
EISSN:
1097-4164
ISSN:
1097-2765
URN:
uuid:5215d9a8-5c78-4119-8369-5ca5bc05cd23
Source identifiers:
209814
Local pid:
pubs:209814

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