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Sleep homeostasis and cortical synchronization: III. A high-density EEG study of sleep slow waves in humans.

Abstract:

STUDY OBJECTIVES: The mechanisms responsible for the homeostatic decrease of slow-wave activity (SWA, defined in this study as electroencephalogram [EEG] power between 0.5 and 4.0 Hz) during sleep are unknown. In agreement with a recent hypothesis, in the first of 3 companion papers, large-scale computer simulations of the sleeping thalamocortical system showed that a decrease in cortical synaptic strength is sufficient to account for the decline in SWA. In the model, the reduction in SWA wa...

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Authors


Riedner, BA More by this author
Vyazovskiy, VV More by this author
Massimini, M More by this author
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Journal:
Sleep
Volume:
30
Issue:
12
Pages:
1643-1657
Publication date:
2007-12-05
EISSN:
1550-9109
ISSN:
0161-8105
URN:
uuid:51ff09a9-2704-49de-8e3c-f4d5ad152c20
Source identifiers:
456120
Local pid:
pubs:456120

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