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Effects of weight loss on myocardial energetics and diastolic function in obesity

Abstract:

A reduced myocardial phosphocreatine/adenosine triphosphate (PCr/ATP) ratio is linked to both diastolic dysfunction and heart failure. Although obesity is well known to cause diastolic dysfunction a link to impaired cardiac energetics has only recently been established. We assessed whether or not long-term weight loss in obesity, which is known to reduce mortality, is accompanied by both improved cardiac energetics and diastolic function. Normal weight (BMI 22 ± 2; n = 18) and obese subjects ...

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Publisher copy:
10.1007/s10554-012-0174-6

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Journal:
International Journal of Cardiovascular Imaging
Volume:
29
Issue:
5
Pages:
1043-1050
Publication date:
2013-06-05
DOI:
EISSN:
1573-0743
ISSN:
1569-5794
URN:
uuid:51f02f9f-8d4c-4fd3-b392-649f43de896e
Source identifiers:
449150
Local pid:
pubs:449150

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