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An exploratory analysis of the response to ChAdOx1 nCoV-19 (AZD1222) vaccine in males and females

Abstract:
Background There are known differences in vaccine reactogenicity and immunogenicity by sex. Females have been shown to report greater reactogenicity and generate higher humoral and cellular immune responses than males following vaccination with several different vaccines. Whether this is also the case for COVID-19 vaccines is currently unknown, as COVID-19 vaccine study data disaggregated by sex are not routinely reported. Therefore, we have assessed the influence of sex on r... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.ebiom.2022.104128

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author
ORCID:
0000-0002-0749-8329
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
ORCID:
0000-0003-0746-1945
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Contributors

Publisher:
Elsevier Publisher's website
Journal:
eBioMedicine Journal website
Volume:
81
Article number:
104128
Publication date:
2022-06-29
Acceptance date:
2022-06-08
DOI:
EISSN:
2352-3964
Pmid:
35779491
Language:
English
Keywords:
Pubs id:
1266472
Local pid:
pubs:1266472
Deposit date:
2022-07-27

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