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Journal article

Re-activated adult epicardial progenitor cells are a heterogeneous population molecularly distinct from their embryonic counterparts.

Abstract:

Cardiovascular disease remains the major cause of mortality, and cardiac cell therapy has recently emerged as a paradigm for heart repair. The epicardium is a layer of mesothelial cells covering the heart that during development contributes to different cardiovascular lineages, including cardiomyocytes, but which becomes quiescent after birth. We previously revealed that the peptide thymosin beta 4 (Tβ4) can reactivate adult epicardium-derived cells (EPDCs) after myocardial infarction (MI), t...

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Publication status:
Published

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Publisher copy:
10.1089/scd.2014.0019

Authors


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Institution:
University of Oxford
Division:
MSD
Role:
Author
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Journal:
Stem cells and development
Volume:
23
Issue:
15
Pages:
1719-1730
Publication date:
2014-08-01
DOI:
EISSN:
1557-8534
ISSN:
1547-3287
Source identifiers:
462090
Language:
English
Keywords:
Pubs id:
pubs:462090
UUID:
uuid:51e2d107-4c9b-426c-bcd5-d3afbc3321d2
Local pid:
pubs:462090
Deposit date:
2015-01-16

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