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Journal article

Re-activated adult epicardial progenitor cells are a heterogeneous population molecularly distinct from their embryonic counterparts.

Abstract:

Cardiovascular disease remains the major cause of mortality, and cardiac cell therapy has recently emerged as a paradigm for heart repair. The epicardium is a layer of mesothelial cells covering the heart that during development contributes to different cardiovascular lineages, including cardiomyocytes, but which becomes quiescent after birth. We previously revealed that the peptide thymosin beta 4 (Tβ4) can reactivate adult epicardium-derived cells (EPDCs) after myocardial infarction (MI), t...

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Publication status:
Published

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Publisher copy:
10.1089/scd.2014.0019

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Institution:
University of Oxford
Department:
Oxford, MSD
Role:
Author
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Journal:
Stem cells and development
Volume:
23
Issue:
15
Pages:
1719-1730
Publication date:
2014-08-05
DOI:
EISSN:
1557-8534
ISSN:
1547-3287
URN:
uuid:51e2d107-4c9b-426c-bcd5-d3afbc3321d2
Source identifiers:
462090
Local pid:
pubs:462090

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