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Colon salvage therapy for acute severe colitis: cyclosporine or infliximab?

Abstract:

PURPOSE OF REVIEW: Steroid-refractory acute severe colitis (ASC) poses a significant clinical challenge to both physicians and surgeons alike. This review highlights advances in management of these patients and the role of cyclosporine compared to infliximab. RECENT FINDINGS: ASC affects 25% of patients with ulcerative colitis and is associated with measurable morbidity and mortality. Simple clinical and laboratory measures predict steroid refractoriness (such as stool frequency 3-8/day and ...

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Publication status:
Published

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Authors


Burger, DC More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Journal:
Current opinion in gastroenterology
Volume:
27
Issue:
4
Pages:
358-362
Publication date:
2011-07-05
DOI:
EISSN:
1531-7056
ISSN:
0267-1379
URN:
uuid:51dae495-ca36-4ae4-bbc2-59dc834251e5
Source identifiers:
127172
Local pid:
pubs:127172

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