Colon salvage therapy for acute severe colitis: cyclosporine or infliximab?
PURPOSE OF REVIEW: Steroid-refractory acute severe colitis (ASC) poses a significant clinical challenge to both physicians and surgeons alike. This review highlights advances in management of these patients and the role of cyclosporine compared to infliximab. RECENT FINDINGS: ASC affects 25% of patients with ulcerative colitis and is associated with measurable morbidity and mortality. Simple clinical and laboratory measures predict steroid refractoriness (such as stool frequency 3-8/day and ...Expand abstract
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