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Changes in sodium channel expression following trigeminal nerve injury.

Abstract:

We have investigated the expression of TTX-sensitive (TTXs) and TTX-resistant (TTXr) sodium channel subtypes following injury to the inferior alveolar nerve (IAN), in order to determine their potential role in the development of trigeminal neuropathic pain. In seven anaesthetised ferrets, fluorogold (2%) was injected into the left IAN to identify cell bodies with axons in this nerve. In four animals, the nerve was sectioned distal to the injection site and the remaining three served as contro...

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Publication status:
Published

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Authors


Davies, SL More by this author
Loescher, AR More by this author
Clayton, NM More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Structural Genomics Consortium
Robinson, PP More by this author
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Journal:
Experimental neurology
Volume:
202
Issue:
1
Pages:
207-216
Publication date:
2006-11-05
DOI:
EISSN:
1090-2430
ISSN:
0014-4886
URN:
uuid:51cdc533-1fd8-4df3-80be-a9a12601745b
Source identifiers:
33577
Local pid:
pubs:33577

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