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Fibrillin: from domain structure to supramolecular assembly.

Abstract:

In the last 5 years, significant progress has been made in understanding the structure and function of all the major domains composing the fibrillins. A previous review [Meth. Enzymol. 245 (1994), 29] focused on the isolation of fibrillin monomers and fibrillin-containing polymers (microfibrils). In this article, information gained from recent studies which have further elucidated molecular structure and investigated effects of mutations on structural and functional properties will be summari...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Downing, AK More by this author
Reinhardt, DP More by this author
Journal:
Matrix biology : journal of the International Society for Matrix Biology
Volume:
19
Issue:
6
Pages:
457-470
Publication date:
2000-11-05
DOI:
EISSN:
1569-1802
ISSN:
0945-053X
URN:
uuid:51cdb9e3-213f-4364-af29-3bdb1bf1a4a3
Source identifiers:
100281
Local pid:
pubs:100281

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