Journal article icon

Journal article

Accelerated evolution of the Prdm9 speciation gene across diverse metazoan taxa.

Abstract:

The onset of prezygotic and postzygotic barriers to gene flow between populations is a hallmark of speciation. One of the earliest postzygotic isolating barriers to arise between incipient species is the sterility of the heterogametic sex in interspecies' hybrids. Four genes that underlie hybrid sterility have been identified in animals: Odysseus, JYalpha, and Overdrive in Drosophila and Prdm9 (Meisetz) in mice. Mouse Prdm9 encodes a protein with a KRAB motif, a histone methyltransferase doma...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1371/journal.pgen.1000753

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Role:
Author
More by this author
Institution:
University of Oxford
Role:
Author
Expand authors...
More from this funder
Funding agency for:
Goodstadt, L
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS genetics Journal website
Volume:
5
Issue:
12
Article number:
e1000753
Publication date:
2009-12-01
DOI:
EISSN:
1553-7404
ISSN:
1553-7390
Source identifiers:
68163
Language:
English
Keywords:
Pubs id:
pubs:68163
UUID:
uuid:51bf1da8-e53d-429d-820a-b3ad04fbc3c9
Local pid:
pubs:68163
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP