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Medical research council trial of antilymphocyte globulin in renal transplantation. A multicenter randomized double-blind placebo controlled clinical investigation.

Abstract:

A total of 173 patients who received live donor or cadaveric primary or secondary renal transplants at five British hospitals were entered into a randomized double-blind controlled clinical trial of equine antilymphocyte globulin (ALG) administered prophylactically to prevent rejection. The ALG was prepared in the early 1970s and used cultured human lymphoblasts as antigen. Following transplantation all patients were treated with a standard immunosuppressant regimen of steroids and azathiopri...

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Publication status:
Published

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Authors


Blamey, RW More by this author
Briggs, JD More by this author
Castro, JE More by this author
Hamilton, DN More by this author
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Journal:
Transplantation
Volume:
35
Issue:
6
Pages:
539-545
Publication date:
1983-06-05
DOI:
EISSN:
1534-6080
ISSN:
0041-1337
URN:
uuid:51916800-0d75-43c4-87eb-24ce7373977d
Source identifiers:
42270
Local pid:
pubs:42270

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