Journal article icon

Journal article

Membrane compartmentalization reduces the mobility of lipids and proteins within a model plasma membrane

Abstract:

The cytoskeleton underlying cell membranes may influence the dynamic organization of proteins and lipids within the bilayer by immobilizing certain transmembrane (TM) proteins and forming corrals within the membrane. Here we present coarse-grained resolution simulations of a biologically realistic membrane model of asymmetrically organized lipids and TM proteins. We determine the effects of a model of cytoskeletal immobilization of selected membrane proteins using long timescale coarse-graine...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

Actions


Access Document


Files:
Publisher copy:
10.1021/acs.jpcb.6b05846

Authors


More by this author
Department:
Christ Church
Role:
Author
More by this author
Department:
Oxford, MSD, Biochemistry
Role:
Author
More by this author
Department:
Oxford, MSD, NDM, NDM Experimental Medicine
Role:
Author
Engineering and Physical Sciences Research Council More from this funder
Biotechnology and Biological Sciences Research Council More from this funder
Edward Penley Abraham Cephalosporin Fund More from this funder
Expand funders...
Publisher:
American Chemical Society Publisher's website
Journal:
Journal of Physical Chemistry Part B Journal website
Volume:
120
Issue:
34
Pages:
8873–8881
Publication date:
2016-08-05
Acceptance date:
2016-08-02
DOI:
EISSN:
1520-5207
ISSN:
1520-6106
Pubs id:
pubs:637270
URN:
uri:51886719-a4bc-428b-85e2-101f017ada2e
UUID:
51886719-a4bc-428b-85e2-101f017ada2e
Local pid:
pubs:637270

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP