- Abstract:
-
The cytoskeleton underlying cell membranes may influence the dynamic organization of proteins and lipids within the bilayer by immobilizing certain transmembrane (TM) proteins and forming corrals within the membrane. Here we present coarse-grained resolution simulations of a biologically realistic membrane model of asymmetrically organized lipids and TM proteins. We determine the effects of a model of cytoskeletal immobilization of selected membrane proteins using long timescale coarse-graine...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted manuscript
- Publisher:
- American Chemical Society Publisher's website
- Journal:
- Journal of Physical Chemistry Part B Journal website
- Volume:
- 120
- Issue:
- 34
- Pages:
- 8873–8881
- Publication date:
- 2016-08-05
- Acceptance date:
- 2016-08-02
- DOI:
- EISSN:
-
1520-5207
- ISSN:
-
1520-6106
- Pubs id:
-
pubs:637270
- URN:
-
uri:51886719-a4bc-428b-85e2-101f017ada2e
- UUID:
-
51886719-a4bc-428b-85e2-101f017ada2e
- Local pid:
- pubs:637270
- Copyright holder:
- American Chemical Society
- Copyright date:
- 2016
- Notes:
- Copyright © 2016 American Chemical Society
Journal article
Membrane compartmentalization reduces the mobility of lipids and proteins within a model plasma membrane
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Engineering and Physical Sciences Research Council
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Biotechnology and Biological Sciences Research Council
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Edward Penley Abraham Cephalosporin Fund
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