Journal article
Membrane compartmentalization reduces the mobility of lipids and proteins within a model plasma membrane
- Abstract:
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The cytoskeleton underlying cell membranes may influence the dynamic organization of proteins and lipids within the bilayer by immobilizing certain transmembrane (TM) proteins and forming corrals within the membrane. Here we present coarse-grained resolution simulations of a biologically realistic membrane model of asymmetrically organized lipids and TM proteins. We determine the effects of a model of cytoskeletal immobilization of selected membrane proteins using long timescale coarse-graine...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Accepted manuscript, pdf, 2.2MB)
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- Publisher copy:
- 10.1021/acs.jpcb.6b05846
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Authors
Funding
Alfred Benzon Foundation
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Engineering and Physical Sciences Research Council
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Biotechnology and Biological Sciences Research Council
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Bibliographic Details
- Publisher:
- American Chemical Society Publisher's website
- Journal:
- Journal of Physical Chemistry Part B Journal website
- Volume:
- 120
- Issue:
- 34
- Pages:
- 8873–8881
- Publication date:
- 2016-08-01
- Acceptance date:
- 2016-08-02
- DOI:
- EISSN:
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1520-5207
- ISSN:
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1520-6106
- Source identifiers:
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637270
Item Description
- Keywords:
- Pubs id:
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pubs:637270
- UUID:
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uuid:51886719-a4bc-428b-85e2-101f017ada2e
- Local pid:
- pubs:637270
- Deposit date:
- 2016-08-03
Terms of use
- Copyright holder:
- American Chemical Society
- Copyright date:
- 2016
- Notes:
- Copyright © 2016 American Chemical Society
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