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Journal article

Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection.

Abstract:

BACKGROUND: HLA-B57, as well as cytotoxic T-lymphocyte (CTL) responses restricted by this allele, have been strongly associated with long-term non-progressive chronic HIV-1 infection. However, their impact on viral replication during acute HIV-1 infection is not known. METHODS: Clinical and immunological parameters during acute and early HIV-1 infection in individuals expressing HLA-B57 were assessed. HIV-1-specific T-cell responses were determined by peptide-specific interferon-gamma produc...

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Publication status:
Published

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Journal:
AIDS (London, England)
Volume:
17
Issue:
18
Pages:
2581-2591
Publication date:
2003-12-05
DOI:
EISSN:
1473-5571
ISSN:
0269-9370
URN:
uuid:5187f7f2-114c-452f-b354-a48f25b23c5e
Source identifiers:
191073
Local pid:
pubs:191073

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