- Abstract:
-
Sensory neurones co-express voltage-gated sodium channels that mediate TTX-sensitive (TTX-S) and TTX-resistant (TTX-R) currents, which may contribute to chronic pain after nerve injury. We previously demonstrated that TTX-R channels were decreased acutely in human sensory cell bodies after central axotomy, but accumulated in nerve terminals after peripheral axotomy. We have now studied the TTX-S channels PN1 and Brain III, using specific antibodies for immunohistochemistry, in dorsal root gan...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1097/00001756-200103050-00014
-
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- Journal:
- Neuroreport
- Volume:
- 12
- Issue:
- 3
- Pages:
- 495-500
- Publication date:
- 2001-03-05
- DOI:
- EISSN:
-
1473-558X
- ISSN:
-
0959-4965
- URN:
-
uuid:517616b9-9220-4816-a901-5aefcf91facf
- Source identifiers:
-
31835
- Local pid:
- pubs:31835
- Copyright date:
- 2001
Journal article
Plasticity of TTX-sensitive sodium channels PN1 and brain III in injured human nerves.
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