Journal article icon

Journal article

Cytochrome c oxidase levels in chondrocytes during monolayer expansion and after return to three dimensional culture.

Abstract:

OBJECTIVE: Here we investigate whether monolayer culture or culture at 21% oxygen influences activity of cytochrome c oxidase, the terminal enzyme in the respiratory chain whose activity is essential for oxidative metabolism and whether return to three dimensional (3-D) culture restores cytochrome c oxidase activity to original levels. METHODS: Primary bovine articular chondrocytes were cultured in alginate beads (3-D) for 4 weeks or in monolayer under 1% and 21% oxygen for up to 9 days and ...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1016/j.joca.2009.03.001

Authors


Boubriak, OA More by this author
Brooks, JT More by this author
Journal:
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society
Volume:
17
Issue:
8
Pages:
1084-1092
Publication date:
2009-08-05
DOI:
EISSN:
1522-9653
ISSN:
1063-4584
URN:
uuid:5170b131-0f77-471e-8c91-d592e267ec29
Source identifiers:
239129
Local pid:
pubs:239129

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP