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Journal article

PCDH11 is X/Y homologous in Homo sapiens but not in Gorilla gorilla and Pan troglodytes.

Abstract:

Protocadherin X (PCDHX) and Protocadherin Y (PCDHY) are cell-surface adhesion molecules expressed predominantly in brain. The human PCDH11X/Y gene pair is located in the non-pseudoautosomal X-Y homologous region (Xq21.3/Yp11.2). The possible existence of PCDH11 gene dosage differences between human and non-human primates is of evolutionary significance with respect to species differences and escape from X inactivation, and has been repeatedly debated. Previous investigations on the X/Y homolo...

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Publication status:
Published

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Publisher copy:
10.1159/000093329

Authors


Wilson, ND More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Journal:
Cytogenetic and genome research
Volume:
114
Issue:
2
Pages:
137-139
Publication date:
2006
DOI:
EISSN:
1424-859X
ISSN:
1424-8581
URN:
uuid:5169c9de-465f-49f9-b7c8-870b03885adf
Source identifiers:
33532
Local pid:
pubs:33532

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