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Cryopreserved Plasmodium vivax and cord blood reticulocytes can be used for invasion and short term culture

Abstract:

The establishment of a Plasmodium vivax in vitro culture system is critical for the development of new vaccine, drugs and diagnostic tests. Although short-term cultures have been successfully set up, their reproducibility in laboratories without direct access to P. vivax-infected patients has been limited by the need for fresh parasite isolates. We explored the possibility of using parasite isolates and reticulocytes, both cryopreserved, to perform invasion and initiate short-term culture. In...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/j.ijpara.2011.10.011

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Publisher:
Elsevier Publisher's website
Journal:
International Journal for Parasitology Journal website
Volume:
42
Issue:
2
Pages:
155-160
Publication date:
2012-02-05
DOI:
EISSN:
1879-0135
ISSN:
0020-7519
URN:
uuid:510bf375-b0c8-4be6-8f86-b356481d12f1
Source identifiers:
313860
Local pid:
pubs:313860

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