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Journal article

Different MHC class I alleles compete for presentation of overlapping viral epitopes.

Abstract:

We previously identified an HLA-B8+ donor, NW, whose lymphoblastoid cells failed to present a B8-restricted epitope from the influenza A nucleoprotein following viral infection, although added peptide could still be presented. The failure to present through HLA-B8 following viral infection appears to be specific for the NP epitope. Here, we report that donor NW makes an HLA-B2702-restricted influenza-specific CTL response to an epitope in the nucleoprotein that overlaps the B8-restricted epit...

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Publication status:
Published

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Journal:
Immunity
Volume:
3
Issue:
1
Pages:
65-77
Publication date:
1995-07-05
DOI:
EISSN:
1097-4180
ISSN:
1074-7613
URN:
uuid:50d604c9-f5cd-4dcf-a007-9ea5b22ae0ea
Source identifiers:
35624
Local pid:
pubs:35624

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