- Abstract:
-
Using immunocytochemistry and in situ hybridization, we have examined the expression of brain-derived neurotrophic factor (BDNF) and of neurotrophin receptors in dorsal root ganglion cells. In the adult rat, BDNF mRNA and protein were found mainly in the subpopulation of cells that express the nerve growth factor (NGF) receptor trkA and the neuropeptide calcitonin gene-related peptide (CGRP). NGF increased BDNF within the trkA/CGRP cells to the extent that almost 90% of trkA cells contained B...
Expand abstract - Journal:
- The Journal of neuroscience : the official journal of the Society for Neuroscience
- Volume:
- 17
- Issue:
- 21
- Pages:
- 8476-8490
- Publication date:
- 1997-11-05
- EISSN:
-
1529-2401
- ISSN:
-
0270-6474
- URN:
-
uuid:50bd753f-8185-40e2-872a-7cd393607f57
- Source identifiers:
-
365811
- Local pid:
- pubs:365811
- Language:
- English
- Keywords:
- Copyright date:
- 1997
Journal article
Nerve growth factor treatment increases brain-derived neurotrophic factor selectively in TrkA-expressing dorsal root ganglion cells and in their central terminations within the spinal cord.
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