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Coherent spike-wave oscillations in the cortex and subthalamic nucleus of the freely moving rat.

Abstract:

The basal ganglia play a critical role in controlling seizures in animal models of idiopathic non-convulsive (absence) epilepsy. Inappropriate output from the substantia nigra pars reticulata (SNr) is known to exacerbate seizures, but the precise neuronal mechanisms underlying abnormal activity in SNr remain unclear. To test the hypothesis that cortical spike-wave oscillations, often considered indicative of absence seizures, propagate to the subthalamic nucleus, an important afferent of SNr,...

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Publication status:
Published

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Authors


Magill, PJ More by this author
Sharott, A More by this author
Harnack, D More by this author
Meissner, W More by this author
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Journal:
Neuroscience
Volume:
132
Issue:
3
Pages:
659-664
Publication date:
2005
DOI:
EISSN:
1873-7544
ISSN:
0306-4522
URN:
uuid:50bc8b17-5379-45d4-95ae-c3750229f2aa
Source identifiers:
70879
Local pid:
pubs:70879

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