Journal article
Lysine methylation and the regulation of p53.
- Abstract:
-
The p53 tumour suppressor protein functions as a guardian against genotoxic stress. This function is mediated in part by the transcriptional activation of genes involved in cell-cycle arrest, apoptosis, DNA repair and autophagy. The activity of p53 is regulated by a complex array of post-translational modifications, which function as a code to determine cellular responses to a given stress. In this chapter we highlight recent advances in our understanding of this code, with particular referen...
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- Publication status:
- Published
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- Publisher copy:
- 10.1042/bse0520079
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Authors
Bibliographic Details
- Journal:
- Essays in biochemistry
- Volume:
- 52
- Issue:
- 1
- Pages:
- 79-92
- Publication date:
- 2012-01-01
- DOI:
- EISSN:
-
1744-1358
- ISSN:
-
0071-1365
- Source identifiers:
-
339980
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:339980
- UUID:
-
uuid:50ab790d-9dec-4307-848b-0cc116d0ee20
- Local pid:
- pubs:339980
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 2012
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