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Journal article

Techniques used to define human MHC antigens: polymerase chain reaction and oligonucleotide probes.

Abstract:

The various HLA class II specificities, identifiable by serological or cellular typing reagents, reflect underlying polymorphisms of the constituent alpha and beta chains, encoded at several loci within the HLA-D region. Variation in these genes is concentrated in allelic hypervariable regions but can also be found elsewhere. Sequence-specific oligonucleotides (SSO) can be used to detect individual alleles with a high degree of accuracy by probing dot-blotted DNA, amplified to high copy numbe...

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Publication status:
Published

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Authors


Wordsworth, P More by this author
Journal:
Immunology letters
Volume:
29
Issue:
1-2
Pages:
37-39
Publication date:
1991-07-05
DOI:
EISSN:
1879-0542
ISSN:
0165-2478
URN:
uuid:50a0aac7-dc46-4f83-a1ea-fbc3f5cebe81
Source identifiers:
108324
Local pid:
pubs:108324

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