Journal article
Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal
- Abstract:
-
Adaptive evolution in humans has rarely been characterized for its whole set of components, i.e. selective pressure, adaptive phenotype, beneficial alleles and realized fitness differential. We combined approaches for detecting polygenic adaptations and for mapping the genetic bases of physiological and fertility phenotypes in approximately 1000 indigenous ethnically Tibetan women from Nepal, adapted to high altitude. The results of genome-wide association analyses and tests for polygenic ada...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 4.2MB)
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- Publisher copy:
- 10.1371/journal.pgen.1007650
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Authors
Funding
National Science Foundation
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Dartmouth College
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University of Chicago
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Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS Genetics Journal website
- Volume:
- 14
- Issue:
- 9
- Pages:
- e1007650
- Publication date:
- 2018-09-06
- Acceptance date:
- 2018-08-21
- DOI:
- ISSN:
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1553-7390 and 1553-7404
- Pmid:
-
30188897
- Source identifiers:
-
915446
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:915446
- UUID:
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uuid:509dd4e2-cf68-45ea-9f70-73802ba01bd2
- Local pid:
- pubs:915446
- Deposit date:
- 2018-11-20
Terms of use
- Copyright holder:
- Jeong et al
- Copyright date:
- 2018
- Notes:
- © 2018 Jeong et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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