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Tutorial: The practical application of longitudinal structural equation mediation models in clinical trials

Abstract:

The study of mediation of treatment effects, or how treatments work, is important to understanding and improving psychological and behavioral treatments, but applications have often focused on mediators and outcomes measured at a single time point. Such crosssectional analyses do not respect the implied temporal ordering that mediation suggests. Clinical trials of treatments often provide repeated measures of outcomes and, increasingly, of mediators as well. A trial with repeated measurements...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1037/met0000154

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Department:
St Cross College
Role:
Author
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Publisher:
American Psychological Association Publisher's website
Journal:
Psychological Methods Journal website
Volume:
23
Issue:
2
Pages:
191-207
Publication date:
2017-12-28
Acceptance date:
2017-05-22
DOI:
EISSN:
1939-1463
ISSN:
1082-989X
Pubs id:
pubs:699001
URN:
uri:504a4547-392a-4654-89c7-ec48cf5eef16
UUID:
uuid:504a4547-392a-4654-89c7-ec48cf5eef16
Local pid:
pubs:699001

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