- Abstract:
-
CONTEXT: Multiple endocrine neoplasia type 1 (MEN1) is characterized by the occurrence of parathyroid, pituitary, and pancreatic tumors. MEN1, an autosomal dominant disorder, has a high degree of penetrance, such that more than 95% of patients develop clinical manifestations by the fifth decade, although this is lower at approximately 50% by age 20 yr. However, the lower penetrance in the younger group, which is based on detecting hormone-secreting tumors, may be an underestimate because pati...
Expand abstract - Publication status:
- Published
- Journal:
- The Journal of clinical endocrinology and metabolism
- Volume:
- 94
- Issue:
- 10
- Pages:
- 3640-3646
- Publication date:
- 2009-10-05
- DOI:
- EISSN:
-
1945-7197
- ISSN:
-
0021-972X
- URN:
-
uuid:502d134d-c8aa-4f6d-bef9-22f5a1b4be20
- Source identifiers:
-
34804
- Local pid:
- pubs:34804
- Language:
- English
- Keywords:
- Copyright date:
- 2009
Journal article
Asymptomatic children with multiple endocrine neoplasia type 1 mutations may harbor nonfunctioning pancreatic neuroendocrine tumors.
Actions
Authors
Bibliographic Details
Item Description
Terms of use
Metrics
Altmetrics
Dimensions
If you are the owner of this record, you can report an update to it here: Report update to this record