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Relationship of the K-ras/c-mos expression patterns with angiogenesis in non-small cell lung carcinomas.

Abstract:

BACKGROUND: Neo-angiogenesis is an acquired capability vital for a tumor to grow and metastasize. Evidence has shown that the mitogen-activated protein (MAP) kinase pathway is involved in this process. Alterations of K-ras and c-mos, two pivotal components of this pathway, have been implicated in non-small cell lung carcinogenesis. In the present report, we examine, in a series of non-small cell lung carcinomas (NSCLCs), the status of K-ras and c-mos oncoproteins in correlation with the tumor...

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Publication status:
Published

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Authors


Zacharatos, P More by this author
Kotsinas, A More by this author
Tsantoulis, P More by this author
Evangelou, K More by this author
Kletsas, D More by this author
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Journal:
Molecular medicine (Cambridge, Mass.)
Volume:
7
Issue:
9
Pages:
590-597
Publication date:
2001-09-05
EISSN:
1528-3658
ISSN:
1076-1551
URN:
uuid:5021c89b-7bea-4923-9400-b4ecaea050c4
Source identifiers:
324033
Local pid:
pubs:324033

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