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Journal article

Effects of hydrocortisone on brain 5-HT function and sleep.

Abstract:

The effects of hydrocortisone administration (20 mg, orally, twice daily) on the sensitivity of brain 5-HT1A receptors in healthy volunteers were studied using a buspirone challenge paradigm. The effects of hydrocortisone administration on sleep architecture were also studied. Hydrocortisone treatment significantly attenuated the hypothermic and cortisol responses to buspirone; however, the prolactin and growth hormone responses were unchanged. Hydrocortisone also decreased the amount of rapi...

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Publication status:
Published

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Authors


Sharpley, AL More by this author
Campling, GM More by this author
Hockney, RA More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Journal:
Journal of affective disorders
Volume:
32
Issue:
2
Pages:
139-146
Publication date:
1994-10-05
DOI:
EISSN:
1573-2517
ISSN:
0165-0327
URN:
uuid:501e57ff-0ec5-405d-a3de-78ba77efe6dc
Source identifiers:
185998
Local pid:
pubs:185998

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