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Tendinopathy and tears of the rotator cuff are associated with hypoxia and apoptosis.

Abstract:

The aim of this study was to investigate the occurrence of tissue hypoxia and apoptosis at different stages of tendinopathy and tears of the rotator cuff. We studied tissue from 24 patients with eight graded stages of either impingement (mild, moderate and severe) or tears of the rotator cuff (partial, small, medium, large and massive) and three controls. Biopsies were analysed using three immunohistochemical techniques, namely antibodies against HIF-1alpha (a transcription factor produced in...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
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Journal:
The Journal of bone and joint surgery. British volume
Volume:
92
Issue:
3
Pages:
448-453
Publication date:
2010-03-05
DOI:
ISSN:
0301-620X
URN:
uuid:4ff1b892-6eb3-4b26-851b-da9dde151fb1
Source identifiers:
103900
Local pid:
pubs:103900

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