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Mixed treatment comparison meta-analysis evaluating the relative efficacy of nucleos(t)ides for treatment of nucleos(t)ide-naive patients with chronic hepatitis B.

Abstract:

BACKGROUND/AIMS: Five nucleoside/nucleotide treatments are now available for chronic hepatitis B (CHB). This meta-analysis aimed to assess the relative efficacy of adefovir, entecavir, lamivudine, telbivudine, tenofovir disoproxil fumarate (TDF), and nucleos(t)ide combinations in the treatment of CHB. METHODS: A systematic review of MEDLINE and the Cochrane library was conducted to identify all studies evaluating these nucleos(t)ides in adults with CHB. Randomized controlled trials were incl...

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Publication status:
Published

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Journal:
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research
Volume:
13
Issue:
8
Pages:
934-945
Publication date:
2010-12-05
DOI:
EISSN:
1524-4733
ISSN:
1098-3015
URN:
uuid:4fd3c6e2-0441-4cc0-9fe1-08a48fc8a99c
Source identifiers:
202202
Local pid:
pubs:202202

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