Journal article icon

Journal article

RvE1 attenuates polymicrobial sepsis-induced cardiac dysfunction and enhances bacterial clearance

Abstract:

The development of cardiac dysfunction caused by microbial infection predicts high mortality in sepsis patients. Specialized pro-resolving mediators (SPMs) mediate resolution of inflammation in many inflammatory diseases, and are differentially expressed in plasma of sepsis patients. Here, we investigated whether the levels of SPMs are altered in the murine septic heart following polymicrobial sepsis-induced cardiac dysfunction. Ten weeks-old male C57BL/6 mice were subjected to polymicrobial ...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Expand authors...
Publisher:
Frontiers Media Publisher's website
Journal:
Frontiers in Immunology Journal website
Volume:
11
Article number:
2080
Publication date:
2020-09-02
Acceptance date:
2020-07-30
DOI:
EISSN:
1664-3224
Pmid:
32983159
Pubs id:
1133725
Local pid:
pubs:1133725
Language:
English
Keywords:
Format:
Electronic-eCollection

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP