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Unravelling the fetal origins hypothesis: is there really an inverse association between birthweight and subsequent blood pressure?

Abstract:

BACKGROUND: The association between birthweight and subsequent blood pressure levels has been considered to provide some of the strongest, and most consistent, support for the "fetal origins" hypothesis of adult disease. It had been estimated that a 1 kg higher birthweight is typically associated with a 2-4 mm Hg lower systolic blood pressure. METHODS: 55 studies that had reported regression coefficients of systolic blood pressure on birthweight (with 48 further studies that reported only th...

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Publication status:
Published

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Journal:
Lancet
Volume:
360
Issue:
9334
Pages:
659-665
Publication date:
2002-08-05
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
URN:
uuid:4fc53e7c-dc62-41e9-b947-cc3300a808f3
Source identifiers:
49231
Local pid:
pubs:49231

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