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Embryonic stem cells: a novel source of dendritic cells for clinical applications.

Abstract:

As arbitrators of the immune response, dendritic cells (DC) are uniquely placed to negotiate the balance between the opposing forces of tolerance and immunity, making them attractive candidates for clinical applications. Accordingly, DC have been used successfully in the treatment of cancer, enhancing immune responses to tumour-associated antigens (TAA) in experimental animal models and phase I clinical trials. A novel source of DC that has recently been described is the embryonic stem (ES) c...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Cartland, S More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Volume:
5
Issue:
1
Pages:
13-21
Publication date:
2005-01-05
DOI:
EISSN:
1878-1705
ISSN:
1567-5769
URN:
uuid:4fc32152-45e7-442d-8168-3d3faee8a7cf
Source identifiers:
16877
Local pid:
pubs:16877

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