- Abstract:
-
Airway ciliary beat frequency regulation is complex but in part influenced by cyclic adenosine monophosphate (cAMP)-mediated changes in cAMP-dependent kinase activity, yet the cAMP concentration required for increases in ciliary beat frequency and the temporal relationship between ciliary beat frequency and cAMP changes are unknown. A lentiviral gene transfer system was developed to express a fluorescence resonance energy transfer (FRET)-based cAMP sensor in ciliated cells. Expression of fluo...
Expand abstract - Publisher copy:
- 10.1242/jcs.03181
-
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- Journal:
- Journal of cell science
- Volume:
- 119
- Issue:
- Pt 20
- Pages:
- 4176-4186
- Publication date:
- 2006-10-05
- DOI:
- EISSN:
-
1477-9137
- ISSN:
-
0021-9533
- URN:
-
uuid:4f9965e0-3682-4141-8e69-418963835b23
- Source identifiers:
-
237842
- Local pid:
- pubs:237842
- Language:
- English
- Keywords:
- Copyright date:
- 2006
Journal article
Real-time analysis of cAMP-mediated regulation of ciliary motility in single primary human airway epithelial cells.
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