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Polymer packaging and ejection in viral capsids: shape matters.

Abstract:

We use a mesoscale simulation approach to explore the impact of different capsid geometries on the packaging and ejection dynamics of polymers of different flexibility. We find that both packing and ejection times are faster for flexible polymers. For such polymers a sphere packs more quickly and ejects more slowly than an ellipsoid. For semiflexible polymers, however, the case relevant to DNA, a sphere both packs and ejects more easily. We interpret our results by considering both the thermo...

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Publication status:
Published

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Authors


Marenduzzo, D More by this author
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Institution:
University of Oxford
Department:
Oxford, MPLS, Physics, Theoretical Physics
Journal:
Physical review letters
Volume:
96
Issue:
20
Pages:
208102
Publication date:
2006-05-05
DOI:
EISSN:
1079-7114
ISSN:
0031-9007
URN:
uuid:4f8574dd-0842-43b3-b1dd-33f7530321d5
Source identifiers:
25453
Local pid:
pubs:25453

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