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Journal article

Hepatitis C virus: life cycle in cells, infection and host response, and analysis of molecular markers influencing the outcome of infection and response to therapy

Abstract:

Hepatitis C virus (HCV) is a major global health burden accounting for around 170 million chronic infections worldwide. Since its discovery, which dates back to about 30 years ago, many details of the viral genome organization and the astonishing genetic diversity have been unveiled but, owing to the difficulty of culturing HCV in vitro and obtaining fully susceptible yet immunocompetent in vivo models, we are still a long way from the full comprehension of viral life cycle, host cell pathway...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.cmi.2016.08.025

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
Publisher:
Elsevier Publisher's website
Journal:
Clinical microbiology and infection Journal website
Volume:
22
Issue:
10
Pages:
826-832
Publication date:
2016-08-31
Acceptance date:
2016-08-25
DOI:
EISSN:
1469-0691
ISSN:
1198-743X
Pmid:
27592089
Source identifiers:
641873
Language:
English
Keywords:
Pubs id:
pubs:641873
UUID:
uuid:4f446995-19bb-4e35-9ddc-05895dba001c
Local pid:
pubs:641873
Deposit date:
2016-09-09

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