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Long-term efficacy of sulfonylureas: a United Kingdom Prospective Diabetes Study perspective.

Abstract:

The United Kingdom Prospective Diabetes Study shows sulfonylureas to be an effective first-line therapy for people with type 2 diabetes mellitus. The durability of the glycemic control obtained is dependent on the degree to which beta-cell function can be maintained, but sulfonylureas appear neither to increase nor to decrease the underlying rate of loss of beta-cell function. As sulfonylureas act by enhancing insulin secretion, they are probably best used close to the time when diabetes is d...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM, Biomedical Research Centre
Role:
Author
Volume:
55
Issue:
5 Suppl 1
Pages:
S2-S5
Publication date:
2006-05-05
DOI:
EISSN:
1532-8600
ISSN:
0026-0495
URN:
uuid:4f2a1180-273c-40e3-ad41-dcb0c32a5feb
Source identifiers:
10354
Local pid:
pubs:10354

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