Cellular distribution of p68, a new calcium-binding protein from lymphocytes.

Journal article

A Ca2+-binding protein of mol. wt. 68 000 ( p68 ) is a major component of a Nonidet P-40 insoluble fraction of human and pig lymphocyte plasma membrane. An affinity-purified rabbit antibody has been produced against p68 and used to study its cellular distribution. The antibody stained fixed and permeabilised human B lymphoblastoid cells, peripheral blood lymphocytes and sections of human tonsil. Whole cells, however, were not stained, indicating that the protein was not represented at the cel...

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Authors: Owens, R; Gallagher, C; Crumpton, M

• Publication status: Published
• Journal: EMBO journal
• Volume: 3
• Issue: 5
• Pages: 945-952
• Publication date: 1984-05-01
• EISSN: 1460-2075
• ISSN: 0261-4189
• Language: English
• Keywords: Molecular Weight; Humans; Antibodies; Mice; Leukemia, Lymphoid; Cell Fractionation; Chromatography, Affinity; Animals; Cell Line; Palatine Tonsil; Hybridomas; Subcellular Fractions; Leukemia; Cell Membrane; Calcium-Binding Proteins; Fluorescent Antibody Technique; Lymphocytes