Journal article icon

Journal article

Biochemical characterization and cellular imaging of a novel, membrane permeable fluorescent cAMP analog

Abstract:

Background: A novel fluorescent cAMP analog (8-[Pharos-575]- adenosine-3', 5'-cyclic monophosphate) was characterized with respect to its spectral properties, its ability to bind to and activate three main isoenzymes of the cAMP-dependent protein kinase (PKA-Iα, PKA-IIα, PKA-IIβ) in vitro, its stability towards phosphodiesterase and its ability to permeate into cultured eukaryotic cells using resonance energy transfer based indicators, and conventional ...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1186/1471-2091-9-18

Authors


Publisher:
BioMed Central Publisher's website
Journal:
BMC Biochemistry Journal website
Volume:
9
Article number:
18
Publication date:
2008-06-25
Acceptance date:
2008-06-25
DOI:
EISSN:
1471-2091
Source identifiers:
237753
Language:
English
Keywords:
UUID:
uuid:4ef915e6-d4a0-4111-8b31-5037dd9b1f5a
Local pid:
pubs:237753
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP