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Vitamin D threshold to prevent aromatase inhibitor-related bone loss: the B-ABLE prospective cohort study.

Abstract:

Aromatase inhibitor (AI)-related bone loss is associated with increased fracture rates. Vitamin D might play a role in minimising this effect. We hypothesised that 25-hydroxy-vitamin D concentrations [25(OH)D] after 3 months supplementation might relate to bone loss after 1 year on AI therapy. We conducted a prospective cohort study from January 2006 to December 2011 of a consecutive sample of women initiating AI for early breast cancer who were ineligible for bisphosphonate therapy and staye...

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Publication status:
Published

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Publisher copy:
10.1007/s10549-012-2013-9

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Servitja, S More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Garrigós, L More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
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Journal:
Breast cancer research and treatment
Volume:
133
Issue:
3
Pages:
1159-1167
Publication date:
2012-06-05
DOI:
EISSN:
1573-7217
ISSN:
0167-6806
URN:
uuid:4eed2615-8572-4fb0-9a26-988ff90acaee
Source identifiers:
344615
Local pid:
pubs:344615

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