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Primaquine toxicity forestalls effective therapeutic management of the endemic malarias

Abstract:

Treatment of acutely ill patients, informed by a diagnosis of the species of Plasmodium involved, has long dominated strategic thinking in malaria chemotherapeutics. This bias for both acute illness and access to diagnosis resulted in therapeutic strategies poorly suited to malaria as it occurs in endemic zones. Most of those malarias do not provoke illness and occur beyond diagnostic reach for technical or practical reasons. Therapies effective against all species and stages would likely pro...

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Journal:
International Journal for Parasitology
Volume:
42
Issue:
12
Pages:
1049-1054
Publication date:
2012-11-05
DOI:
EISSN:
1879-0135
ISSN:
0020-7519
URN:
uuid:4ee2551d-578d-48a6-90cc-56a7e6c37746
Source identifiers:
366753
Local pid:
pubs:366753

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