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Genetic analysis of vitamin D related genes in Canadian multiple sclerosis patients

Abstract:

The objective of this study was to investigate genes involved in the metabolism and function of vitamin D as candidate genes for genetic susceptibility to MS. Restriction fragment length polymorphisms and highly polymorphic microsatellite markers within or very close to the 1,25(OH)2D3 receptor (VDR) [12q14], the vitamin D binding protein (DBP) [4q12], and the 25(OH)D3 1α-hydroxylase [12q13] loci were analyzed for linkage or association with MS. We found no evidence for linkage or association...

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Publication status:
Published

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Journal:
NEUROLOGY
Volume:
54
Issue:
3
Pages:
729-732
Publication date:
2000-02-08
ISSN:
0028-3878
URN:
uuid:4edd01c9-d046-4e8f-b95c-030a76235ae7
Source identifiers:
37369
Local pid:
pubs:37369
Language:
English
Keywords:

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