Journal article
No association of coronary artery disease with x-chromosomal variants in comprehensive international meta-analysis
- Abstract:
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In recent years, genome-wide association studies have identified 58 independent risk loci for coronary artery disease (CAD) on the autosome. However, due to the sex-specific data structure of the X chromosome, it has been excluded from most of these analyses. While females have 2 copies of chromosome X, males have only one. Also, one of the female X chromosomes may be inactivated. Therefore, special test statistics and quality control procedures are required. Thus, little is known about the r...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 388.9KB, Terms of use)
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- Publisher copy:
- 10.1038/srep35278
Authors
Funding
+ German Federal Ministry of Education and Research (BMBF)
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Grant:
01ZX1313A-2014
Bibliographic Details
- Publisher:
- Springer Nature
- Journal:
- Scientific Reports More from this journal
- Volume:
- 6
- Pages:
- 35278
- Publication date:
- 2016-10-12
- Acceptance date:
- 2016-09-26
- DOI:
- ISSN:
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2045-2322
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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pubs:652915
- UUID:
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uuid:4eabe6c4-3674-4cf4-b9cc-967e68f2d071
- Local pid:
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pubs:652915
- Source identifiers:
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652915
- Deposit date:
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2016-12-01
Terms of use
- Copyright holder:
- Loley et al
- Copyright date:
- 2016
- Notes:
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© The Author(s) 2016. This work is licensed under a Creative Commons Attribution 4.0 International License. The images
or other third party material in this article are included in the article’s Creative Commons license,
unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license,
users will need to obtain permission from the license holder to reproduce the material. To view a copy of this
license, visit http://creativecommons.org/licenses/by/4.0/. This is the publisher's version of the article. The final version is available online from [publisher] at: https://doi.org/[DOI if we have it]”*
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