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Interleukin 7 and interleukin 4 stimulate human thymocyte growth through distinct mechanisms.

Abstract:

One of the major functions of cytokines is their ability to regulate cell growth and differentiation. The complexity of this process has been highlighted by recent studies on murine thymocytes; it has been shown that a number of cytokines interact to regulate thymocyte growth. We have investigated the effects of interleukin 4 (IL-4) and interleukin 7 (IL-7) on human thymocyte proliferation. Although maximal proliferation was dependent upon the presence of the mitogen phytohaemagglutinin (PHA)...

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Authors


Chantry, D More by this author
Brennan, F More by this author
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Journal:
Cytokine
Volume:
2
Issue:
1
Pages:
55-59
Publication date:
1990-01-05
DOI:
EISSN:
1096-0023
ISSN:
1043-4666
URN:
uuid:4e9b094c-9560-4cfc-8b10-1813718a96a5
Source identifiers:
481757
Local pid:
pubs:481757

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