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Modeling tuberculosis dynamics with the presence of hyper-susceptible individuals for Ho Chi Minh City from 1996 to 2015

Abstract:

Background

The depletion of CD4 cell is the underlying reason for TB hyper-susceptibility among people with HIV. Consequently, the trend of TB dynamics is usually hidden by the HIV outbreak.

Methods

Here, we aim to evaluate the trend of TB dynamics quantitatively by a simple mathematical model using the known prevalence of hyper-susceptible individuals in the population. In order to estimate the parameters governing transmission we fit this model in a maximum like...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/s12879-018-3383-3

Authors


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ORCID:
0000-0002-4424-1557
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
Tropical Medicine
ORCID:
0000-0002-2858-2087
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
Tropical Medicine
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Funding agency for:
Thwaites, G
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Funding agency for:
Thuong, NTT
TDModNet Seed Funding Program More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
BMC Infectious Diseases Journal website
Volume:
18
Issue:
1
Pages:
494
Publication date:
2018-10-01
Acceptance date:
2018-09-13
DOI:
EISSN:
1471-2334
ISSN:
1471-2334
Pubs id:
pubs:923709
URN:
uri:4e96b433-921c-42d5-8103-37a2c91825e2
UUID:
uuid:4e96b433-921c-42d5-8103-37a2c91825e2
Local pid:
pubs:923709

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